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Jun Guo Selected Research

Temozolomide (Temodar)

1/2023Camrelizumab Plus Apatinib and Temozolomide as First-Line Treatment in Patients With Advanced Acral Melanoma: The CAP 03 Phase 2 Nonrandomized Clinical Trial.
1/2022Exosomes Derived from Hypoxic Glioma Cells Reduce the Sensitivity of Glioma Cells to Temozolomide Through Carrying miR-106a-5p.
1/2022Phase II study of apatinib combined with temozolomide in patients with advanced melanoma after failure of immunotherapy.
1/2021Chemotherapy combined with antiangiogenic drugs as salvage therapy in advanced melanoma patients progressing on PD-1 immunotherapy.
5/2019miR-let-7b and miR-let-7c suppress tumourigenesis of human mucosal melanoma and enhance the sensitivity to chemotherapy.
10/2018Safety and Efficacy of Apatinib Combined with Temozolomide in Advanced Melanoma Patients after Conventional Treatment Failure.
8/2013Phase II randomized trial comparing high-dose IFN-α2b with temozolomide plus cisplatin as systemic adjuvant therapy for resected mucosal melanoma.

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Jun Guo Research Topics

Disease

157Neoplasms (Cancer)
05/2024 - 01/2003
117Melanoma (Melanoma, Malignant)
06/2024 - 06/2007
37Infections
04/2024 - 02/2008
33Inflammation (Inflammations)
03/2024 - 08/2007
29Neoplasm Metastasis (Metastasis)
05/2024 - 08/2008
29Ischemia
03/2024 - 03/2003
23Disease Progression
05/2024 - 07/2011
22Brain Ischemia (Cerebral Ischemia)
11/2023 - 03/2003
21Myocardial Infarction
04/2024 - 08/2007
21Renal Cell Carcinoma (Grawitz Tumor)
01/2023 - 02/2008
19Glioma (Gliomas)
01/2024 - 04/2006
18Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
05/2024 - 01/2012
18Breast Neoplasms (Breast Cancer)
01/2024 - 07/2010
15Cardiovascular Diseases (Cardiovascular Disease)
03/2024 - 01/2013
15Hypertension (High Blood Pressure)
01/2023 - 08/2005
15Hypoxia (Hypoxemia)
01/2023 - 07/2012
14Pain (Aches)
11/2023 - 11/2012
14Insulin Resistance
10/2020 - 01/2014
13Stomach Neoplasms (Stomach Cancer)
04/2024 - 05/2008
12Thrombosis (Thrombus)
05/2024 - 01/2006
12Carcinoma (Carcinomatosis)
11/2023 - 03/2007
12COVID-19
02/2023 - 01/2020
12Carcinogenesis
01/2023 - 07/2005
11Necrosis
10/2018 - 05/2002
10Prostatic Neoplasms (Prostate Cancer)
09/2023 - 03/2007
9Fibrosis (Cirrhosis)
04/2024 - 02/2010
9Coronary Artery Disease (Coronary Atherosclerosis)
03/2024 - 01/2017
9Edema (Dropsy)
12/2023 - 04/2006
8Adenocarcinoma of Lung
02/2024 - 01/2015
8Hepatocellular Carcinoma (Hepatoma)
11/2023 - 05/2012
8Glioblastoma (Glioblastoma Multiforme)
01/2020 - 10/2013
7Atrial Fibrillation
05/2024 - 03/2012
7Wounds and Injuries (Trauma)
04/2024 - 02/2011
7Sepsis (Septicemia)
01/2024 - 01/2020
7Pneumonia (Pneumonitis)
01/2023 - 08/2016
7Diarrhea
01/2023 - 01/2014
7Ischemic Stroke
01/2023 - 12/2009
7Colorectal Neoplasms (Colorectal Cancer)
01/2023 - 08/2012
7Stroke (Strokes)
01/2023 - 09/2009
7Type 2 Diabetes Mellitus (MODY)
01/2022 - 05/2010
7Body Weight (Weight, Body)
01/2022 - 11/2013
6ST Elevation Myocardial Infarction
11/2023 - 08/2005
6Acute Kidney Injury (Acute Renal Failure)
06/2023 - 01/2016
6Heart Failure
01/2023 - 06/2017
6Infarction (Infarctions)
01/2023 - 08/2007

Drug/Important Bio-Agent (IBA)

70Proteins (Proteins, Gene)FDA Link
12/2023 - 10/2003
27Biomarkers (Surrogate Marker)IBA
05/2024 - 01/2015
23MicroRNAs (MicroRNA)IBA
04/2024 - 01/2012
18Glucose (Dextrose)FDA LinkGeneric
11/2023 - 09/2010
17CalciumIBA
01/2022 - 03/2003
16Messenger RNA (mRNA)IBA
03/2024 - 07/2004
15Phosphotransferases (Kinase)IBA
01/2024 - 07/2003
15AntigensIBA
02/2023 - 03/2010
14Therapeutic UsesIBA
01/2023 - 01/2007
14CytokinesIBA
10/2019 - 08/2007
13VaccinesIBA
12/2023 - 05/2012
13LipidsIBA
10/2023 - 01/2011
12InterferonsIBA
02/2023 - 07/2011
11AntibodiesIBA
01/2024 - 01/2019
10Immune Checkpoint InhibitorsIBA
01/2024 - 01/2020
10Small Interfering RNA (siRNA)IBA
01/2023 - 05/2004
9Tyrosine Kinase InhibitorsIBA
05/2024 - 07/2011
9salicylhydroxamic acid (SHAM)IBA
12/2023 - 07/2003
9RNA (Ribonucleic Acid)IBA
11/2023 - 12/2011
9Interleukin-6 (Interleukin 6)IBA
01/2022 - 08/2007
8Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
03/2024 - 03/2008
8omega-Chloroacetophenone (Mace)IBA
03/2024 - 11/2013
8Oxygen (Dioxygen)IBA
01/2024 - 09/2010
8apatinibIBA
01/2023 - 10/2018
8Immunoglobulin G (IgG)IBA
01/2023 - 01/2020
8Cisplatin (Platino)FDA LinkGeneric
01/2022 - 05/2011
8Sunitinib (Sutent)FDA Link
03/2020 - 08/2013
8CeramidesIBA
12/2015 - 09/2008
7Immunoconjugates (Immunoconjugate)IBA
05/2024 - 10/2017
7toripalimabIBA
03/2024 - 11/2019
7Indicators and Reagents (Reagents)IBA
03/2024 - 01/2011
7Monoclonal AntibodiesIBA
02/2023 - 12/2014
7Temozolomide (Temodar)FDA LinkGeneric
01/2023 - 08/2013
7LigandsIBA
01/2023 - 10/2013
7EverolimusFDA Link
01/2023 - 02/2012
7Mitogen-Activated Protein KinasesIBA
01/2023 - 10/2003
7Reactive Oxygen Species (Oxygen Radicals)IBA
12/2020 - 02/2008
7Sorafenib (BAY 43-9006)FDA Link
01/2019 - 11/2012
7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2018 - 04/2006
7KetamineFDA LinkGeneric
05/2013 - 03/2003
7N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
09/2010 - 03/2003
6human ERBB2 proteinIBA
01/2024 - 01/2011
6SodiumIBA
11/2023 - 07/2012
6EnzymesIBA
12/2022 - 01/2009
6Axitinib (AG 013736)IBA
01/2022 - 01/2015
6Doxorubicin (Adriamycin)FDA LinkGeneric
01/2022 - 04/2007

Therapy/Procedure

134Therapeutics
06/2024 - 01/2005
42Drug Therapy (Chemotherapy)
05/2023 - 07/2005
41Immunotherapy
03/2024 - 05/2012
12Stents
05/2024 - 03/2006
9Percutaneous Coronary Intervention
03/2024 - 11/2011
9Transplantation
02/2019 - 08/2007
8Radiotherapy
03/2024 - 07/2010
7Chinese Traditional Medicine (Traditional Chinese Medicine)
04/2024 - 01/2009
7Aftercare (After-Treatment)
10/2022 - 12/2008